Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette Required for proper attachment of

Required for proper attachment of the midbody to the cell membrane during cytokinesis

mitotic checkpoint protein) contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein

Alternative splicing results in multiple transcript variants encoding distinct isoforms

mediation of synaptic function and cell survival after ischemia

May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity

Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette Required for proper attachment ofCell surface proteoglycan that bears heparan sulfate (By similarity). Negatively regulates the hedgehog signaling pathway when attached via the GPI anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By similarity). Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (By similarity). Positively regulates the canonical